Andrew H. posted an article on Brain Windows - Nov 11, 2009, 10:21 pm
Here is an interesting paper, Imaging chromophores with undetectable fluorescence by stimulated emission microscopy, from Sunny Xie’s group.  They pump the sample with a excitation laser while...
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Andrew H. posted an article on Brain Windows - Nov 9, 2009, 5:54 pm
Three papers are out online in Nature Methods that show big improvements in calcium imaging with genetically encoded sensors.  They are are based on the fluorescence intensity indicator, GCaMP.   GC...
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Andrew H. posted an article on Brain Windows - Oct 14, 2009, 1:21 pm
Most people play Quake with a computer mouse, but researchers in David Tank’s lab at Princeton have done it with a living mouse, AND they are recording the intracellular activity of individual n...
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Andrew H. posted an article on Brain Windows - Oct 2, 2009, 6:04 pm
One of the most time consuming and frustrating tasks associated with fluorescence imaging in the brain is picking out your regions of interest.  Which pixels do you include in as part of the cell and...
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Andrew H. posted an article on Brain Windows - Sep 18, 2009, 2:40 pm
Speaking of reactivating specific memories, at the 2009 Society for Neuroscience meeting, Matteo Rizzi of Michael Häusser’s lab is presenting the realization of an idea that has been floating a...
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Andrew H. posted an article on Brain Windows - Sep 16, 2009, 11:06 am
A fully genetically-encoded approach to light-activated transcription is getting closer now that a new, generalizable method of light-switchable protein interactions has been published.  In Nature&...
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Andrew H. posted an article on Brain Windows - Jul 27, 2009, 10:28 am
I have been itching to post about this work since David DiGregorio presented it at a meeting at Janelia last year. His group’s results, Submillisecond Optical Reporting of Membrane Potentials In...
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Andrew H. posted an article on Brain Windows - Jul 22, 2009, 2:11 pm
Annual Reviews of Neuroscience published their 2009 issue recently.  These articles are usually a great way to catch up with a field, particularly when they are recently published.  Here are a few t...
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Andrew H. posted an article on Brain Windows - Jul 16, 2009, 9:17 am
A big advance in non-invasive neuronal remote control was published today in Neuron. Several groups have been working on expressing non-endogenous or customized receptors into neurons so that specific...
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Andrew H. posted an article on Brain Windows - Jul 15, 2009, 10:14 am
Every week or two one of the post-doc’s in our lab passes around a paper that is as much philosophy of science as experimental result.  One that recently made the rounds is Can a Biologist Fix ...
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Andrew H. posted an article on Brain Windows - Jul 14, 2009, 11:48 pm
Mark Schnitzer, who recently became an HHMI Investigtor, has a new paper out on improved optics for his group’s miniature probe microscopes.  Mark has been pioneering these tiny probes to do op...
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Andrew H. posted an article on Brain Windows - Jul 14, 2009, 10:46 pm
Looks like there has been some new results in the field of photoactivated transcription.  Unlike the fully genetically-encoded systems reviewed in a Journal Club, this uses a hybrid genetic and small...
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