... "Things I Won't Work With" stamp on them, at least as far as making them on scale and actually isolating them, some readers pointed out that people were investigating them for antimalarial activity. And here we are, with a new paper in J. Med. Chem. on their activity and properties. Arterolane is the lead compound, which is in Phase III trials as a combination therapy. And it has ...

... in patients with malaria treated with artemisinin combination therapies. "These drugs are designed to kill the parasites within 24 to 48 hours, but we ... resistance problem." Ringwald added that artemisinin resistance is particularly problematic because there are few antimalarial drugs currently in development that could, if necessary, replace artemisinin in terms of effectiveness. However ...

... question. (See Hydroxychloroquine and Risk of Diabetes in Patients With Rheumatoid Arthritis) Antimalarial drugs, like hydroxychloroquine (Plaquenil) which is commonly used in autoimmune diseases such rheumatoid arthritis ... for more than 4 years, a finding that is comparable or superior to that of other drugs studied in clinical trials: rosiglitazone, combination hormone therapy, estrogen only, ...

... In fact, when scientists test anti-anxiety drugs on rats, they use a whiff of cat urine to induce neurochemical ... other organisms. They often have pharmacological effects and are used as medications and recreational drugs. Examples are the local anesthetic and stimulant cocaine, ... stimulant caffeine, nicotine, the analgesic morphine, or the antimalarial drug quinine. Some alkaloids have a bitter taste ...