Postdoctoral Fellowship Drosophila Neurobiology Job Description : We are seeking a talented Post-Doc to address the molecular and cellular basis of synaptic plasticity in functionally impaired synaptic populations in Drosophila. Applicants should have a Ph.D, M.D., or equivalent doctoral degree with at least 3 years of research experience in neurobiology, ...

... synthetase 1 (SPS1/SelD) is an essential gene in Drosophila, its function has not been determined. To elucidate its intracellular role, we targeted the removal of SPS1/SelD mRNA in Drosophila SL2 cells using RNA interference technology that led ... in glutamine synthesis presumably by activating GS1. Our results indicate that, in Drosophila, SPS1/SelD regulates the intracellular glutamine by ...

Background: Proper patterning of the follicle cell epithelium over the egg chamber is essential for the Drosophila egg development. Differentiation of the epithelium into several distinct cell types along the anterior-posterior ... pathways. Previously, we reported that lethal(2)giant larvae (lgl), a Drosophila tumor suppressor gene, is required in the follicle cells for the posterior follicle cell ( ...

They say that time flies like an arrow, but fruit flies like a banana. As I type this, I am surrounded by a small cloud of flying insects. To my right, a glass of Wolf Blass Yellow Label Chardonnay is crawling with the little buggers. They don't dart around like the blue-arsed flies, banging their heads against the windows in idiot desperation. Nor do they patrol with humming menace like the ...

... mice and SCA3 patient brain tissue. However, the pathological significance of Ataxin-3 cleavage has not been carefully examined. To gain insight into the significance of Ataxin-3 cleavage, we developed a Drosophila SL2 cell-based model as well as transgenic fly models. Our data indicate that Ataxin-3 protein cleavage is conserved in the fly and may be caspase-dependent as reported previously. ...

... a labile to a stable state after training by a process termed consolidation. Further, the memory process can be strongly affected by motivational state. Using olfactory memory in the fruit fly Drosophila as a model, and applying state-of-the-art genetic manipulations, Dr. Waddell’s laboratory studies the mechanisms by which memory is encoded and stabilized at the molecular, cellular and neural ...

Vasa (Vas) is a DEAD-box RNA-binding protein required in Drosophila at several steps of oogenesis and for primordial germ cell (PGC) specification. Vas associates with eukaryotic initiation factor 5B (eIF5B), and this interaction has been implicated in translational activation of gurken mRNA in the oocyte. Vas is expressed in all ovarian germline cells, and aspects of the vas-null phenotype ...

... of mitochondria and nuclear genomes, she transplanted mitochondria from different species into Drosophila melanogaster. These have between 18 and 100 amino acid substitutions from ... new downstream targets to, for instance, regulate epidermal rotations. Drosophila are old, and many of these species differences are millions of years old. They are now looking at more recently diverged species ...

... gene schlank (German for slim). With the fruit fly Drosophila there is a rather paradox convention. Together with Dr. Reinhard Bauer and ... . Humans also produce ceramide synthases however not just one as Drosophila does but rather as many as six different ones. For this purpose humans rely on a group of genes so ... family controls growth and body fat in Drosophila….Read the Full Story Related ...

... that makes this model harder to stick with. The researchers look at fruit flies, Drosophila, the very pest that I'm trying to evict from my kitchen at home (thanks to a recent ... Full feeding thus increases fecundity and decreases lifespan through the effects of different nutrients in Drosophila, the fecundity increase through methionine alone and the lifespan decrease through a combination of ...

Drosophila melanogaster (from Wikimedia Commons via Futurity) Fruit Flies and Musical Language Some interesting research ... fruit flies and music. The first, out of Caltech, used the humble little Drosophila melanogaster (only about 2.5mm in size) to study ... model the attention deficits of schoolchildren in a fly, Drosophila proves again and again that its relatively simple brain (with only 200,000 ...

Control of neuroblast maintenance in Drosophila by signaling pathways The project will center on the long term maintenance of the proliferative capacity of Drosophila neuroblasts and how this is affected by signalling pathways, including Notch, Hedgehog, Wnt and RTKs. Positions include interdisciplinary training, summer schools and yearly international meetings. Qualification To be considered ...

... hyperactivity disorder (ADHD). Caltech researchers said that the brain of the fruit fly Drosophila contains only about 20,000 neurons, or nerve cells, and has long been ... behavior as learning, memory, courtship and metabolism otherwise known as circadian rhythm. But they are not yet sure whether the Drosophila brain could also be used to study the genetic basis of "emotional" behavior.

... ) have uncovered evidence of a primitive emotion-like behavior in the fruit fly, Drosophila melanogaster. Their findings, which may be relevant to the relationship between the neurotransmitter dopamine and attention deficit hyperactivity disorder (ADHD), are described in the December issue of the journal Neuron. The Drosophila brain contains only about 20,000 neurons and

... Moss Plants and More has an interesting post with regard to Physcomitrella patens, the model organism moss. Which, just like Drosophila and even worst, is not monophylous (the issue with Drosophila was mostly on taxonomic grounds, this one may really be at odds with the science results behind…). From No seeds, no fruits, no flower, you may reach a new fern ...