... . JRA, also called juvenile idiopathic arthritis (JIA) or juvenile chronic arthritis (JCA), can be mild, ... pain medicine, and limits on physical activity to ongoing arthritis and the need for major surgery such as joint replacement. But for most adults ... significant disabilities. Some children with polyarthritis develop arthritis in the neck that can cause the neck bones to fuse together. A child ...

... of Extremely Skewed X Chromosome Inactivation In Juvenile Idiopathic Arthritis Juvenile idiopathic arthritis (JIA) is a childhood rheumatic disease of unknown etiology. Two subgroups of JIA, i.e., oligoarticular and polyarticular, ... disorders occurring predominantly in females. As a result, a study published in Arthritis & Rheumatism (2009;60:3410-3412), was ...

... serious adverse events (SAE). To assess the safety of adalimumab in rheumatoid arthritis (RA) over time and across five other immune-mediated inflammatory diseases and to compare ... to adalimumab in 36 global clinical trials in RA, psoriatic arthritis (PsA), ankylosing spondylitis (AS), Crohn’s disease (CD), psoriasis and juvenile idiopathic arthritis (JIA) to 15 April 2007. Events per 100 ...

... from a late-stage trial of Actemra for systemic onset Juvenile Idiopathic Arthritis (sJIA), a disease that causes intermittent fever, rash, and arthritis symptoms. The drug--a potential blockbuster--met its primary endpoint by ... FDA declined to approve the drug for the treatment of rheumatoid arthritis, delaying it for at least 18 months. The company said full data and safety ...